Shown are microscopic images of human epidermis with pluripotent stem cells derived from donated skin cells. The images on the left are epidermis from a healthy control subject, the images at ...

As a self-renewing organ maintained by multiple distinct stem cell populations, the skin epidermis represents an outstanding, clinically highly relevant research paradigm to address these questions.

The skin epidermis has become the paradigm for exploring ... Figure 2: Potential mechanisms for p63 maintaining stem-cell populations.

The findings of Taylor et al. 1 indicate that epidermis can be produced by hair follicles in undamaged newborn skin, and that stem cell progeny move horizontally from the follicle, a process that ...