DNA replication is one of the most basic processes ... Meanwhile, as the helicase separates the strands, another enzyme called primase briefly attaches to each strand and assembles a foundation ...

LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

During DNA replication, the unwinding of strands leaves ... effective approach is to find proteins that directly bind to both enzymes. However, that requires us to understand the molecular ...

DNA replication is the process by which the DNA molecule makes an exact copy of itself during cell division. The double helix unwinds, and each strand serves as a template for the synthesis of a new ...

The repair enzymes are remarkably conserved from bacteria to fungi to humans, underscoring the premium placed on maintaining genomic integrity in the face of a mutagenic burden. DNA is susceptible to ...

Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...

Zhijian “James” Chen, a biochemist at the University of Texas Southwestern Medical Center, was awarded the 2024 Albert Lasker Basic Medical Research Award for the discovery of the cGAS enzyme that ...

Announcing a new article publication for Zoonoses journal. Methicillin resistant Staphylococcus aureus (MRSA) and Vancomycin ...

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

During DNA replication, the complementary base pairing of thymine with adenine ensures the accurate copying of genetic information. DNA polymerase enzymes use the existing DNA strand as a template and ...

At any location, it is thought likely RNA replication preceded the ... dye to their nucleic acids and adding enzymes that ...

This dimerization inhibits DNA replication, which may lead to death of the organism ... Photoreactivation (light repair): The photoreactivation repair enzyme (PRE) is activated by visible light ...