A team of researchers, led by Professor Chae Un Kim from the Department of Physics at UNIST, has successfully tracked the catalytic pathway of carbonic anhydrase II (CAII), an enzyme that converts ...

The molecules that form the foundation of life on Earth are as diverse as they are complex. Among these, carbohydrates play a ...

The study of DNMT3A structure with substrates has long been hindered by the difficulty in producing a stable enzyme-substrate complex. "To overcome this challenge, we successfully developed a ...

Considering the geometry of such an enzyme-substrate-complex, they identified three golden rules that should be considered to build a functional enzyme. First, the interface of both enzyme and ...

This equation shows that an enzyme and a substrate bind to form an enzyme-substrate complex (ES). This complex then produces the product. As the enzyme is released at the end and not used up in ...

The biosynthesis of the great variety of natural plant products has not yet been elucidated for many medically interesting substances. In a new study, an international team of researchers was able to ...

The enzyme (blue) binds to its substrate (red) to form an enzyme-substrate complex. The enzyme then catalyzes the conversion of the substrate into products (pink), which are released. The enzyme ...

The study of DNMT3A structure with substrates has long been hindered by the difficulty in producing a stable enzyme-substrate complex. "To overcome this challenge, we successfully developed a ...