Once the cofactor is added, the enzyme becomes the active “holoenzyme”. Cofactors can either be ions, such as zinc and iron ions, or organic molecules, such as vitamins or vitamin-derived ...

Finally, enzymes of the sulphite oxidase family contain haem cofactors. Recently, another link between the metabolic pathways of molybdenum and iron was discovered. In plants (and most probably ...

Tryptophan, which naturally contains rings with conjugated bonds, needs the fewest changes to become a quinone cofactor. "Although several enzymes are known to contain a quinone cofactor derived ...

One enzyme that requires such assembly is the HYDA1 enzyme, which contains a complex cofactor, which is the area inside the enzyme where the actual hydrogen production takes place. The cofactor ...

The researchers used site-specific mutagenesis to gain new insights into how the cofactor precursor is integrated into the enzyme and how individual amino acids are involved in anchoring and ...

Researchers from Osaka University have streamlined the traditionally slow process of enzyme engineering. This work might help researchers tailor the suitability of enzymes for custom purposes ...

Of these glutathione peroxidase is an enzyme containing four selenium-cofactors that catalyzes the breakdown of hydrogen peroxide and organic hydroperoxides. Glutathione ''S''-transferases show ...

The researchers used site-specific mutagenesis to gain new insights into how the cofactor precursor is integrated into the ...

The team “didn’t imagine” that the enzyme itself would directly use light for catalysis, he says. FAP contains flavin adenine dinucleotide (FAD), which commonly serves as a redox cofactor in ...

Researchers have identified how such a cofactor, the so-called hydrogen cluster, is assembled. Specifically, they describe the previously unexplained role of the enzyme HydF, which is involved in ...