For decades, scientists have studied how to control DNA—the molecule that holds the instructions for all life. One of the ...

Single-stranded DNA repair is a critical process whose mechanism has never been determined. Now, researchers have figured out how this process works, focusing on an enzyme associated with the ...

Restriction enzymes, which allow scientists to cut ... "The next big step is to cleave double-stranded DNA targets." The National Institutes of Health, the Defense Threat Reduction Agency, and ...

Production of endonucleolytic double-strand DNA breaks requires separate ... Type ISP restriction-modification (RM) enzymes, which cleave random DNA between distant target sites when two enzymes ...

such as ionizing radiation (IR), cause detrimental DNA damage called DNA double-strand breaks (DSBs), which, if not repaired efficiently and accurately, can lead to loss of genome integrity ...

An INRS team discovers a new family of enzymes capable of ... A form of DNA with a key role Single-stranded DNA is less common than double-stranded DNA. It is often found in some viruses and ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together ... More —like superglue— and creates a safe zone for other proteins to come repair the damage.

Developed from a derivative of the immune system of bacteria, CRISPR enables double strands of ... based on a family of specific enzymes called Ssn that allows targeted cuts to be induced exclusively ...

coli bacteria as it replicated and measure how fast enzyme machinery worked on the different strands. The DNA double helix is made from two strands that run in opposite directions. Each strand is made ...

Restriction enzymes, which allow scientists to cut and paste portions ... “The next big step is to cleave double-stranded DNA targets.” with the Breaking Science News daily newsletter ...