SLC35B1 transports ATP into the ER, and its structure offers potential for targeted therapies in diseases linked to ER stress ...

ERAD substrates are degraded by the proteasome, a large ... number of links between the ERAD pathway and human diseases have been identified. Protein folding in the endoplasmic reticulum (ER ...

The endoplasmic reticulum is the protein-making ... seen in nature because it maximizes the cell's ability to make a large number of proteins while minimizing the energetic cost to the cell ...

was also impaired and negatively correlated to endoplasmic reticulum stress and inflammation in patients with diabetes. "In an increasing number of diseases we are finding links between stress and ...

Each organelle also has an outer membrane. Next to the nucleus are enormous, interconnected sacs called the endoplasmic reticulum or ER. From your shrunken view, each sac is only a few inches ...