One FDA-approved treatment is Xiaflex (collagenase clostridium histolyticum), an injectable medication initially used to ...

Without treatment, a minor overuse injury can turn ... or surgical removal of the cyst. Dupuytren's contracture is a condition of unknown origin in which one or more fingers become permanently ...

See how this hand and finger disease affects everyday activities and how to get relief. WebMD shows you Dupuytren's contracture causes, symptoms, and treatments.

Dupuytren (DOO-puh-tren ... disease will need an intervention to relieve the contracture. There are several treatment options. An enzyme injection is a newer, less invasive treatment.

Connext, a clinical stage biotechnology company, announced the successful completion of the dose escalation (Phase 1) part of its Phase 1/2 clinical trial for CNT201, its recombinant collagenase ...

Objectives: To determine if rock climbing is a significant factor in the development of Dupuytren’s disease in men, and, if so, what is the most likely related factor. Methods: Questionnaires were ...

Currently, Endo's Xiaflex is the only commercially available collagenase injection for Dupuytren's contracture. CNT201 is being developed as an alternative to Xiaflex and is expected to significantly ...

- Plans for Phase 2 initiation in Q3 2025 and expansion into Peyronie's disease SEOUL, South Korea, May 7, 2025 /PRNewswire/ -- Connext, a clinical stage biotechnology company, announced the ...

CNT201 offers a new non-surgical treatment option for patients with Dupuytren's contracture. We aim to complete global new drug development with Phase 3 entry in 2027 and demonstrate the unique ...