“In the present study, we found that downregulation of angulin-1/LSR induced malignancy via upregulation of EGF-dependent CLDN-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma.

By combining analysis of patient samples with CRISPR-DiR technology, we found that demethylation and up-regulation of an oncogene after treatment with a hypomethylating agent can indeed occur and ...

Caption The downregulation of miR-124-3p and concurrent upregulation of BDNF suggest a potential regulatory role of miR-124-3p in modulating BDNF expression during SCI. These findings provide new ...

Immune checkpoint molecular upregulation is linked with chronicity and severity of chronic plaque psoriasis, whereas downregulation is linked with poor prognosis of guttate psoriasis. Reviewed by ...

The expression of ORF3a led to fragmentation of the Golgi apparatus, which subsequently led to downregulation of surface MHC-I since the trafficking of glycoproteins to the cell surface was blocked.