The expression of vascular endothelial growth factor (VEGF) is characteristic of differentiated thyroid cancer and is associated with aggressive tumor behavior and a poor clinical outcome.

Preoperative ultrasound to avoid missing metastases in differentiated thyroid cancer. ScienceDaily . Retrieved April 28, 2025 from www.sciencedaily.com / releases / 2013 / 10 / 131016095843.htm ...

Poorly differentiated thyroid cancer is more clinically aggressive and can be challenging to treat. These cancers can spread (metastasizes) to the neck lymph nodes, lungs, and bones. Poorly ...

Papillary and follicular thyroid cancers are considered well-differentiated cancers ... Around 80-90% of thyroid cancer cases are papillary cancer. Papillary cancer can spread to the lymph nodes in ...

This cancer has recently been reclassified ... Hence, the biologic underpinnings of metastatic, differentiated thyroid cancers offer two potential strategies for systemic treatment: disrupting ...

It will spread often by invading into the tissues of the neck, or by spreading through the blood stream into other sites including the bone and other soft tissues as well. Poorly differentiated ...

Well-differentiated cancer cells have specialized structures and tend to grow and spread slowly. Papillary and follicular thyroid cancers are well-differentiated. Undifferentiated cancers are the ...

There’s good evidence, though not perfect quality, that patients with well-differentiated thyroid cancer that has spread beyond the neck—especially in young people with capillary thyroid cancer with ...

Complete remission of differentiated thyroid cancer was more likely in patients ... results showed that extrathyroidal extension, distant metastases, and lack of metformin treatment were ...

More information: Helena Rodríguez-Lloveras et al, DNA Methylation Dynamics and Prognostic Implications in Metastatic Differentiated Thyroid Cancer, Thyroid (2025). DOI: 10.1089/thy.2024.0303 ...

Severity increases with each stage until stage 4, at which point the cancer has spread the furthest. It is also worth noting that with differentiated thyroid cancer (papillary or follicular), age ...