Diastolic heart failure is defined clinically when signs and symptoms of heart failure are present in the presence of preserved left ventricular systolic function (ejection fraction >45%).

Heart failure with normal systolic function has been equated to diastolic heart failure (DHF). DHF appears to be quite common in the elderly, especially in elderly women with hypertension.

Heart failure is a syndrome, not a specific disease, and occurs as a final common pathway in multiple disease states. The section presents a review of diastolic congestive heart failure ...

This can be a normal physiologic change with aging of the heart or result in elevated left atrial pressures leading to the clinical manifestations of diastolic congestive heart failure.

In systolic heart failure, the heart's left lower chamber doesn't contract well, which reduces its force for pumping blood. Diastolic heart failure happens when the left ventricle becomes too ...

Researchers discovered that ALPK2, a heart-specific enzyme, may protect against HFpEF by activating TPM1 in heart muscle ...

Heart failure with preserved ejection function is a lethal form of heart failure, with few effective treatments. A team from ...