Scientists have uncovered how a vitamin A metabolite can suppress anti-cancer immunity. Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have uncovered new ...
MHC class II molecules are central to the adaptive immune response, serving as the means by which antigen-presenting cells, notably dendritic cells, display processed peptides to CD4+ T cells. This ...
Retinoic acid suppresses immune defenses against cancer, but a new drug KyA33 boosts vaccine success and slows tumor growth ...
EPFL researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a ...
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Blocking retinoic acid pathway improves dendritic cell anti-tumor function
Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by ...
New evidence shows that human M cells act as fully fledged antigen-presenting cells, processing and presenting gluten peptides through a dendritic cell-like pathway that may shape early coeliac ...
Trastuzumab deruxtecan (T-DXd) in patients (Pts) with HR-negative HER2-low metastatic breast cancer (mBC): A real-world experience. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I ...
Cancer immunotherapy transforms a patient’s immune cells into a “search‑and‑destroy” force against tumors. But many cancers learn to camouflage themselves from dendritic cells—the immune system’s ...
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