Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists as part of a DNA-protein complex known as chromatin. For this purpose, the ...
A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential ...
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A protein thought to play a supporting role in DNA replication actually facilitates the whole process
Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...
Scientists reveal a hidden second layer of human DNA, showing how genome folding controls genes and influences disease development.
The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible to the cellular machinery that works to express the right genes at the ...
Diagrams: Short section of DNA, 1951 -- Chemical structures of the DNA bases, 1951 -- Covalent bonds of the sugar-phosphate backbone -- Schematic view of a nucleotide -- Mg** ions binding phosphate ...
The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...
An international collaborative research team has discovered that G-quadraplex DNA (G4-DNA) accumulates in neurons and dynamically controls the activation and repression of genes underlying long-term ...
Researchers discovered a kinase-driven phosphorylation switch that activates DNA packaging machinery, aligning nucleosomes at ...
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