Whether it is a microbe, a rose, or a dolphin, any form of life gets its building and operating instructions from the molecule of life, DNA. DNA comprises the genes and chromosomes that govern the ...
However, conditions for DNA replication are rarely ideal. For example, environmental toxins or drugs cause DNA damage and interfere with DNA replication. How does a cell circumvent such problems?
Base substitutions are the simplest type of gene-level mutation, and they involve the swapping of one nucleotide for another during DNA replication. For example, during replication, a thymine ...
A team has unearthed new findings about what happens during the minutes and hours after a cell divides, expanding our understanding of human biology -- and potentially leading to better medicines.
Exonuclease action of replicative polymerase gamma drives damage-induced mitochondrial DNA clearance
How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...
In a groundbreaking shift in our understanding of mutations, researchers have discovered types of DNA damage in healthy cells that can remain unrepaired for years. While most types of DNA damage are ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback