One way they do this is to use a DNA microarray to determine the expression levels of genes. When a gene is expressed in a cell, it generates messenger RNA (mRNA). Overexpressed genes generate ...

Microarrays come in two basic flavours: complementary DNA (cDNA) or oligonucleotide arrays. cDNA arrays can be obtained commercially on filters, or made on glass slides. To compare mRNA levels in ...

DNA tests can tell people where in the world their ancestors came from, and if they're at risk of developing different genetic conditions. They can sometimes even help people connect with family ...

To compare all the genes of one organism to those of another organism, we must first know how to define the entire gene sequence of each organism. However, looking at all of an organism's genes ...

In the 2000s, Young’s team used DNA microarrays, which are glass slides coated with short DNA sequences, to detect genes expressed by cells in response to a variety of stimuli. Although powerful, ...

Microarray Scanners are devices used to measure the fluorescent areas of a DNA microarray to reveal information about the simultaneous activity of thousands of genes. This information can help ...

Scientists use short oligonucleotides as primers for polymerase chain reaction and next-generation sequencing, in DNA microarrays and fluorescence in situ hybridization, and in antisense therapies. (1 ...

Expert Rev Mol Diagn. 2013;13(6):601-611. In other situations, normal microarray analysis in the presence of an abnormal karyotype, such as marker chromosomes, is reassuring, as it indicates that ...