An article by UAB professor Joan-Ramon Daban analyzes in depth the physical problems associated with DNA packaging that have ...

Each of us has enough DNA to reach from here to the sun and back, more than 300 times. How is all of that DNA packaged so tightly into chromosomes and squeezed into a tiny nucleus? Histones are a ...

The common conception of DNA is in long, twisting strands, but in order to fit into the confines of the nucleus, DNA actually condenses into a strict structure called chromatin. Chromatin facilitates ...

To prepare the 46 chromosomes of a human cell for transport to the daughter cells during cell division, each chromosome forms a compact X-shaped structure with two rod-like copies.

DNA is found in nearly all living cells. However, its exact location within a cell depends on whether that cell possesses a special membrane-bound organelle called a nucleus. Organisms composed of ...

Supercoiling as the motor of chromatin loop extrusion Andrzej Stasiak's DNA and Chromosome Modelling Group at SIB set out to understand the nature of the motor that is pushing cohesin along the ...

Chances are you've seen an illustration of DNA's double-helix structure and even pictures of the chromosomes that make up the human genome. But where and how does the famous double helix fit into ...

DNA is perhaps the most famous molecule on earth. Here we explain what it is, what it does, and how it is crucial for health.

Chromatin -- the intertwined histone proteins and DNA that make up chromosomes -- constantly receives messages that pour in from a cell's intricate signaling networks: Turn that gene on. Stifle ...

When chromatin contacts are spaced wider apart on DNA, chromatin loops are larger. Both these parameters are indicators of wider chromosomal arms.