This review describes in detail how some enzymes, such as cytochrome P450, methane monooxygenase, dioxygenases activate dioxygen and selectively transfer oxygen atoms to substrates. The authors ...

Different metalloporphyrin model compounds have been synthesized to study the mechanisms of cytochrome P450s ... the detailed mechanism of the oxygen atom transfer from iodosylarene to the ...

Usually, this job falls to an enzyme called cytochrome P450. Uncontrolled reaction of organic compounds with oxygen is easy: we call it fire. But nature often needs to do oxidations very ...

The cytochrome P450 (CYP) enzymes are a protein superfamily involved in the synthesis and metabolism of drugs, toxins and normal cellular components. The CYP family of enzymes have been identified ...

Cytochrome P450 (CYP450), is a family of hemoglobin-coupled monooxygenases. In mammals, CYP450 oxidizes steroids, fatty acids, and xenobiotics, playing an important role in the metabolism of various ...

and one P450 variant. Professor Jeremy Harvey said: "Our calculations showed that the outcome of the oxygen transfer process (that is, which part of dextromethorphan oxygen gets added to ...

More information: Yukiko Kojima et al, Cytochrome P450 2J2 is required for the natural compound austocystin D to elicit cancer cell toxicity, Cancer Science (2024). DOI: 10.1111/cas.16289 Provided ...

Using stirred-tank bioreactors and control of the dissolved oxygen (DO) concentration ... and inducible cytochrome P450 activity.” Nonetheless, these scientists pushed this method even further.

adding oxygen to a particular carbon atom in a complicated molecule without disturbing anything else. Usually, this job falls to an enzyme called cytochrome P450. Because cytochrome P450 can ...

The name “cytochrome P450 enzymes” is derived due to their several characteristics; they are bound to the membrane of cells (cyto) and contain heme pigment (chrome and P).