The all-too-common deadly disease of young people, cystic fibrosis (CF), is caused by failure of a chloride-ion channel with the unwieldy name of CFTR, standing for cystic fibrosis transmembrane ...

This name posed a problem for those who thought that a chloride channel was primarily responsible for the clinical manifestations of cystic fibrosis. The protein contains 1480 amino acids and a ...

A UB-led research team has developed molecules that could help unclog thick, sticky mucus from the lungs of people suffering from cystic fibrosis. The chronic disease is caused by a defective protein ...

Cystic fibrosis represents one of the most ... This protein functions as a channel that allows chloride ions to move in and out of cells, maintaining proper fluid balance in various organs.

This reduces the function of the chloride channel. What is the most common type of cystic fibrosis? The most common type of cystic fibrosis is delta F508, which is a class 2 protein processing ...

In cystic fibrosis patients, a genetic mutation prevents the CFTR chloride channel from working properly in the mucosal cells of the airways, resulting in very viscous mucus. "Ivacaftor is a drug ...

Cystic fibrosis is a genetic disorder that causes a problem in the channel in your body called the chloride channel and what that does is that it makes it that you get thick secretions in your ...

With more than 70,000 people living with cystic fibrosis (CF) worldwide, according to the Cystic Fibrosis Foundation, the introduction of CF transmembrane conductance regulator (CFTR) modulator ...

In cystic fibrosis patients, a genetic mutation prevents the CFTR chloride channel from working properly in the mucosal cells of the airways, resulting in very viscous mucus. "Ivacaftor is a drug ...