This limit on crossover number, and therefore, recombination, is achieved by crossover interference, a phenomenon through which crossovers inhibit additional crossovers in their vicinity.

Because DSBs give rise to crossovers, their work “gives a plausible, supported solution to a 100-year-old problem central to genetics -- meiotic crossover interference” explained Dr. Smith. It also ...

The application of genetic screen approaches to uncover the crossover interference and inhibition pathway successfully addressed a century-old puzzle in the life sciences.

This limit on crossover number, and therefore, recombination, is achieved by crossover interference, a phenomenon through which crossovers inhibit additional crossovers in their vicinity. However, how ...

image: Joint strategy results in massive increase in genetic recombination. Crossovers, ... how this interference works has remained a mystery since it was first described some 120 years ago.

Crossover interference, where one crossover inhibits the formation of another crossover nearby along the same chromosome, was initially identified by fruit fly geneticist Hermann J. Muller in 1916.

Crossover interference, where one crossover inhibits the formation of another crossover nearby along the same chromosome, was initially identified by fruit fly geneticist Hermann J. Muller in 1916.

As observed more than a century ago by the first geneticists, crossovers inhibit the formation of another crossover nearby on the same chromosome, limiting the number of exchanges between chromosomes.

This limit on crossover number, and therefore, recombination, is achieved by crossover interference, a phenomenon through which crossovers inhibit additional crossovers in their vicinity. However, how ...

New findings from researchers at the Max Planck Institute for Plant Breeding Research in Cologne, Germany, suggest an explanation for the century-old mystery of how chromosome recombination is ...