Caption This cross section of a mouse Colon Chip shows the actin cytoskeleton of epithelial cells in magenta, the overlying mucus in yellow, and the cells' nuclei in blue. The team used this chip ...

(BOSTON) ¬-- Trillions of commensal microbes live on the mucosal and epidermal surfaces of the body and it is firmly established that this microbiome ... an engineered mouse Colon Chip, and ...

Shown is a cross-section of mouse distal colon, with fluorescent staining ... As part of the Urinary Tract Infection Microbiome project, women were recruited to a year-long study that analysed ...

In parallel, they showed that the mouse Colon Chip supported the growth and viability of complex bacterial consortia normally present in mouse and human gut microbiome ... vitro approach could uncover ...

Trillions of commensal microbes live on the mucosal and epidermal surfaces of the body and it is firmly established that this microbiome ... in an engineered mouse Colon Chip, and in a comparative ...

Early nutritional and antibiotic exposures affect adult gut microbiota, with genetic background and parent-of-origin ...

leading to increased bowel inflammation. "Our study provides useful insights on the cross-regulation of the mucosal immune system, epithelial barrier and commensal bacteria not only in humans in ...

This could lead to less invasive screening techniques for colon cancer, particularly for younger patients. "We found four microbiome species profoundly altered in our mouse study," said Shuyun Rao ...

The mouse model is a cornerstone of biological research, used in thousands of studies on a huge range of topics. As we learn more and more about the gut microbiome, its critical importance to and ...

The gut-brain axis is officially a thing. Evidence is accumulating that the gut microbiome, and perturbations in it, can affect behavior—at least in mice. New work is starting to unravel how.

Scientists have harnessed microfluidic organs-on-chip technology to model the different anatomical sections of the mouse intestine and their symbiosis with a complex living microbiome in vitro.