A research team have recently published their article, "Rationally designed pooled CRISPRi-seq uncovers an inhibitor of bacterial peptidyl-tRNA hydrolase" in Cell Reports. In this study ...

Sphere of Influence. In iAssembloids, microglia (red) form projections (white arrows), while astrocytes (green) assume star shapes typically found in the brain. [Courtesy of Kampmann et al., 2025.] ...

CRISPR interference (CRISPRi) is a novel method for specific gene knockdown. It's CRISPR, without the cut. The Horizon CRISPRi system uses a deactivated Cas9 nuclease (dCas9) fused to our proprietary ...

We provide access to CRISPR KO (knockout), CRISPRi (interference) and CRISPRa (activation) technologies, which change the phenotype of cells by eliminating, reducing or increasing gene expression.