NSAIDs variably inhibit prostaglandin H synthase (COX). COX-2 was cloned in 1991, and it was subsequently established that COX-1 does not appear to play a major role in inflammation while COX-2 ...

COX-2 is involved in prostaglandin synthesis and expressed throughout the nervous system, where it participates in pain sensitivity and in synaptic plasticity. Microsomal prostaglandin E synthase ...

Medically reviewed by David Ozeri, MD Prescription anti-inflammatory medications are used to reduce pain, inflammation, and ...

It uses prostaglandin and can have side effects.” One side effect is a change in eye pigmentation. Users with blue eyes have ...

mainly COX-2, and antioxidant properties. In summary, we conclude that resveratrol reduced the prostaglandin formation in neuronal cells probably by inhibiting the activity of inducible PG ...

Figure 1. The formation of AA and LA metabolites (ASA-COX―acetylsalicylic acid (aspirin) cyclooxygenase, PGG―prostaglandin G, LOX―lipoxygenase, HETE―hydroxyeicosatetraenoic acids ...

but involves inhibition of cyclooxygenase (COX-1 and COX-2). Because ibuprofen is also an inhibitor of prostaglandin synthesis, its mode of action may be due to a decrease of prostaglandins in ...