We revealed that the redox cofactor preference of malic enzymes can be strikingly converted by applying phylogenetic analysis to machine learning, without experimental screening. This method can ...

Finally, enzymes of the sulphite oxidase family contain haem cofactors. Recently, another link between the metabolic pathways of molybdenum and iron was discovered. In plants (and most probably ...

More information: Zehui Guo et al, Peptide bridging for cofactor channeling in fusion enzyme lowers cofactor input by two orders of magnitude, Chinese Journal of Catalysis (2025). DOI: 10.1016 ...

has developed a microreactor that efficiently regenerates cofactors through enzyme-catalyzed reactions. "Enzymes are nature's catalysts, but in some cases, enzymes can not prompt a speedy chemical ...

Using this method, they marked the enzyme's cofactor and were able to analyse it in more detail. The tests revealed that the artificial enzyme variant has the same biochemical properties as the ...

Researchers have identified how such a cofactor, the so-called hydrogen cluster, is assembled. Specifically, they describe the previously unexplained role of the enzyme HydF, which is involved in ...

Oxidoreductases are key enzymes in biocatalysis, but their dependence on the cofactor nicotinamide adenine dinucleotide (phosphate) (NAD(P)) presents challenges due to its high consumption and ...