Leiden researchers have discovered an enzyme that helps bacteria feed on everyday plastics. This common enzyme could play a ...

Instead of stabilizing its functional form, the mutated enzyme tends to disrupt communication between the cofactor and the ...

Some enzymes require the addition of another non-protein molecule to function as an enzyme. These are known as cofactors, and without these enzymes remain within the inactive “apoenzyme” forms.

Creating artificial enzymes typically requires either cofactors or complex structural arrangements that precisely position reactive groups in three-dimensional space.

The majority of enzymes are proteins, though some are Ribonucleic acid (RNA) molecules. RNA molecules translate information from DNA and create proteins.

Chemical structure for thiamine pyrophosphate and protein structure of transketolase. Thiamine pyrophosphate cofactor in yellow and xylulose 5-phosphate substrate in black. Credit: Thomas Shafee ...

Spirulina is a nutrient-dense cyanobacterium rich in proteins, phycobiliproteins, carotenoids, and polyphenols that deliver ...

A protein catalyst’s synthetic porphyrin cofactor binds to styrene (light blue) and a diazo compound (pink), which will form a cyclopropane. Enzymes are masters of making molecules.

AI used to design a multi-step enzyme that can digest some plastics Enzyme mechanisms can be complex, and getting them to work is tricky.

Nitrogen is part of many important biomolecules, such as the bases of our DNA and the amino acids that make up proteins and enzymes. Before nitrogen can become part of biomolecules, it must be ...

Instead of stabilizing its functional form, the mutated enzyme tends to disrupt communication between the cofactor and the catalytic site, favoring an inactive conformation.