Results of a real-world study that included people with hemophilia from 33 countries show that people with hemophilia B, ...

These inhibitors can make the standard treatments ... Some patients might experience allergic reactions to their clotting factor treatments, which can range from mild to severe.

A therapy to boost the production of regulatory T-cells prevented inhibitor formation in a mouse model of hemophilia A, per a ...

Preventive treatment options that don't involve the use of FVIII or FIX are needed for patients who develop inhibitors, ...

Hemophilia A and B coagulation defects, which are caused by deficiencies of Factor VIII and Factor IX, respectively, can be bypassed by administration of recombinant Factor VIIa. However, the ...

Gene therapy may have more benefits than just providing clotting factor VIII. A 2023 review suggests gene therapy in hemophilia A can help reduce the presence of inhibitors through a process ...

It’s important that people with hemophilia who use clotting factor concentrates get a blood test for inhibitors at least once a year. If you’re eligible, you can receive free inhibitor testing ...

In participants without inhibitors who received the antithrombin ... compared to those who received on-demand treatment with clotting factor concentrates. Qfitlia has a boxed warning for ...

Patients diagnosed with acquired (autoimmune) hemophilia, a serious and rare bleeding disorder, have high rates of hospital ...

In participants without inhibitors who received fitusiran, there was a 71% reduction in the estimated ABR compared with those who received on-demand treatment with clotting factor concentrates.

Normal blood coagulation (hemostasis ... Development of neutralizing antibodies (inhibitors) may occur. The use of Factor IX-containing products has been associated with the development of ...

Hemophilia A and hemophilia B are genetic bleeding disorders caused by a dysfunction or deficiency of coagulation factor VIII (FVIII) or IX (FIX), respectively. Patients with these hemophilias are ...