Aging, at its most fundamental level, is a molecular process. Chemical marks on the genome shift and lose fidelity over time, ...

A newly identified molecule called OLE helped restore the brain’s immune cells to a more protective state in Alzheimer’s ...

Researchers have successfully demonstrated how astroglia—cells that support the functioning of the brain—can be reprogrammed into cells resembling interneurons. The research, published in Science ...

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

A mechanism underlying neutrophil reprogramming in brain cancers has been uncovered, illuminating potential therapeutic targets to stop their pro-cancer effect. Tumor-infiltrating neutrophils are ...

Researchers have used gene therapy to partially reprogram the brain cells that store memories in aging mice, reversing signs of cellular decline and restoring learning ability. The technique, ...

Brain fog can be scary. It might appear innocently, like losing your car keys or forgetting what date you scheduled that appointment on. Some of this memory loss is normal—it’s just a natural side ...

The next step in the youth quest is a technology called chemical reprogramming. The outspoken longevity scientist David Sinclair has been predicting that one day, you’ll go to the doctor and get a ...

Promising mouse studies and billions of dollars in funding are stoking excitement. But we’ve been here before.

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...