Prometaphase: During this phase, the spindle fibers formed between the centrosomes and the newly made microtubules attach to the kinetochore of each chromosome. Encourage students to modify their ...

The course will be divided into 2 sections. In the first, we will discuss the cell cycle, including checkpoints and regulation, centrosome function, the centromere and kinetochore, and cytokinesis, as ...

Stringent control of the events at the kinetochore–microtubule interface is critical for faithful chromosome segregation. Compton and colleagues now report how a switch in CLASP1-binding ...

Specialized sites on the chromosomes called kinetochores attach to spindle microtubules, and these kinetochore-microtubule attachments are necessary for proper chromosome segregation. Problems in ...

A recent Cell Reports paper by the Oxenius group (IMB) demonstrates a function of targeted centrosome inheritance during CD8 + T cell division for the generation of memory precursor cells.

Because the centrosomes are located outside the nucleus ... During the first part of anaphase, the kinetochore microtubules shorten, and the chromosomes move toward the spindle poles.