Research has recently uncovered a crucial step in the telomerase enzyme catalytic cycle. This catalytic cycle determines the ability of the human telomerase enzyme to synthesize DNA. Research from ...

In all enzyme structures obtained from pyruvate-soaked crystals, we observed well-defined electron densities consistent with a pyruvate molecule in a surface loop close to the entrance of the ...

The researchers determined that a histidine amino-acid residue (His23) in BH32 forms an intermediate called an acyl–enzyme compound during the catalytic cycle. This intermediate is then ...

Research from the laboratory of Professor Julian Chen in the School of Molecular Sciences at Arizona State University recently uncovered a crucial step in the telomerase enzyme catalytic cycle.

Further optimization is achieved through repetition of a Darwinian cycle: 1 ... Directed Evolution of a Designer Enzyme Featuring an Unnatural Catalytic Amino Acid, Angewandte Chemie International ...

With this as a model, Agarwal's team theorized that it should be possible to improve the catalytic efficiency of enzyme reactions by attaching chemical elements on the surface of an enzyme and ...

Pellows et al. use electron paramagnetic (EPR) spectroscopy to characterize photocatalytic E-state intermediates in the catalytic cycle of MoFe protein of the nitrogenase enzyme. Illuminating CdS ...

Among these machines, proteins stand out, with enzymes being the most notable. These catalytic entities dramatically accelerate essential metabolic reactions by many orders of magnitude ...

With this as a model, Agarwal's team theorized that it should be possible to improve the catalytic efficiency of enzyme reactions by attaching chemical elements on the surface of an enzyme and ...