Discover how CRISPR genome editing is revolutionizing medicine. Learn the science of Cas9, current clinical trials, and the future of gene editing.

A recent study utilizing cryo-EM advances our understanding of how bacterial immune systems function and reveals new aspects ...

Scientists have discovered a new CRISPR mechanism with precise activity, expanding the potential applications of the existing CRISPR toolbox. The CRISPR ‘gene scissors’ have become an important basis ...

A novel CRISPR defense mechanism, unlike known nucleases, specifically destroys transfer ribonucleic acids (tRNA) that are vital for protein production to shut down infected cells. (Nanowerk News) ...

In nature, the best-known CRISPR system, CRISPR-Cas9, cuts any RNA or DNA it recognizes as foreign, and thereby protects bacteria from viral attacks. Another CRISPR system, one that is relatively ...

Bacteria and their viruses, known as phages, are locked in an age-old arms race. To defend against phage attacks, bacteria have evolved sophisticated mechanisms to recognize and counteract invading ...

CRISPR/Cas9 is a gene editing tool that has revolutionized biomedical research and led to the first FDA-approved CRISPR-based gene therapy. However, until now, the precise mechanism of exactly how ...

The cryogenic electron microscope structure of the A4p-activated (green) CalpL protein filament (violet) from Candidatus Cloacimonas acidaminovorans (PDB ID: 9EYJ). CRISPR-Cas systems help to protect ...

Banas is associate director of research at the Gene Editing Institute at ChristianaCare, where Kmiec is founder and executive director. The medical promise of CRISPR gene editing can be seen most ...