CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...
When the CRISPR Cas9 protein is added to a cell along with a piece of guide RNA, the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a ...
Nat. Rev. Mol. Cell Biol. 22, 563-579. Our group has determined the crystal structure of the complex formed by anti-CRISPR protein AcrIIA4 and sgRNA-bound type II Cas9. We show that AcrIIA4 ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback