European Medical Journal4h
Aspirin and COX-1 Inhibitors Show Promise in Preventing Cancer Metastasis
Aspirin and COX-1 inhibitors boost immunity against cancer metastasis, revealing a new pathway for anti-metastatic therapies.
Medscape26d
Defining the COX Inhibitor Selectivity of NSAIDs: Implications for Understanding Toxicity
From the crude animal tissue preparations initially used in vitro (e.g., homogenate of guinea ... the differing physiological roles of COX-1 and COX-2, development of 'new' NSAIDs was aimed ...
Medscape1y
Defining the COX Inhibitor Selectivity of NSAIDs: Implications for Understanding Toxicity
For example, nimesulide is a weak competitive inhibitor of COX-1 but a potent ... rapid competitive reversible binding of COX-1 and COX-2 (e.g., ibuprofen, piroxicam, mefenamic acid); Category ...