In chronic low back pain, botulinum neurotoxin type A improved patients' pain and functional outcomes vs placebo and other local injection therapies.

More information: Basavraj Khanppnavar et al, Cryo-EM structure of the botulinum neurotoxin A/SV2B complex and its implications for translocation, Nature Communications (2025). DOI: 10.1038/s41467 ...

Botulinum neurotoxin treatments are mainly used to smooth dynamic wrinkles resulting from facial movements like frowning, ...

Clostridium botulinum produces potent neurotoxins that block neurotransmitter release at femtomolar concentrations, and cause the neuroparalytic syndrome of botulism. So far, molecular details of ...

One form of treatment paused in the UK during the early days of the pandemic was botulinum neurotoxin (BoNT) injections, and as a result some patients have gone months without treatment.

The use of botulinum toxin seems to be a promising and safe approach, particularly in patients at high risk for incontinence. A recent meta-analysis investigated the efficacy of botulinum toxin ...

and genetic regulation of botulinum neurotoxin production and spore formation, stress and adaptive mechanisms, and ecology and cultural dynamics Applied research questions focus on diagnostics and ...

Experts have met to discuss the risks and knowledge gaps around Clostridium botulinum and Clostridium perfringens. At a Food and Agriculture Organization ...

intravesical vanilloids and intradetrusor botulinum neurotoxin type A. The diminishing role of surgical intervention is also discussed.