Bone tissue is a complex structure, consisting of mineralized collagen fibers and a variety of non-collagenous proteins, including proteoglycans such as biglycan and decorin. These proteoglycans ...

What keeps bones able to remodel themselves and stay healthy? A team has discovered clues to the key function of non-collagen protein compounds and how they help bone cells react to external load. The ...

A recent study has uncovered the essential roles of two proteoglycans, biglycan and decorin, in maintaining bone mass, water retention, and bulk/in situ mechanical competence. Through the use of ...

Researchers in Sweden have engineered a cell-free cartilage scaffold that can guide the body to rebuild damaged bone. By removing the cells but preserving the structure and natural growth signals, the ...

Bones consist of an extracellular organic matrix housed in inorganic mineral crystals. The organic matrix is mainly comprised of collagen type 1 amongst other proteins. Bones contain marrow and ...

The researchers were also able to show that it could work in tandem with exercise to strengthen bones even further. Knowing ...

Bone health is a critical aspect of overall well-being, particularly for women. Bones provide structural support, protect vital organs, and allow for mobility. However, as women age, the risk of ...

From hot flashes and night sweats to heart health and digestion, women experience many changes during menopause. One often overlooked effect is a gradual decrease in bone strength and density, which ...