Cholestatic pruritus is a common symptom of primary biliary cholangitis (PBC), a rare autoimmune liver disease. Researchers are looking to establish the safety and efficacy of linerixibat – an ...

Bile duct inflammation and scarring, known as cholangiopathies, can disrupt bile flow, leading to liver damage and ...

In the early stages of primary biliary cholangitis, symptoms occur gradually. The most common initial signs are a feeling of chronic fatigue and pruritus (itchy skin). As primary biliary ...

Itchy skin, or pruritus, can result from conditions like eczema or dermatitis. Less commonly, it can stem from conditions such as kidney failure and liver disease. Some causes of itching affect ...

GSK has reported promising results with a drug to treat the severe itching that plagues patients with rare cholestatic liver disease primary biliary cholangitis (PBC). Interim results from the ...

Patients with PBC not only have severe liver disease and progression but also suffer from significant symptom burden—namely pruritus ... living with primary biliary cholangitis (PBC).” ...

Pruritus is a common symptom that can significantly ... U.S. Indication for Livdelzi Livdelzi is indicated for the treatment of primary biliary cholangitis (PBC) in combination with ...

Biliary tract cancer is a rare adenocarcinoma that occurs in a bile duct, often causing jaundice, pruritus and weight loss. The lesion may be papillary or flat and ulcerated. The tumour is often ...