AMR Action Fund said this morning that the first ... a pipeline of novel combinations of beta-lactam antimicrobials and beta-lactamase inhibitors – drugs used alongside the antibiotics to ...

that may inactivate certain beta-lactamase enzymes. Take with meals. Base dose on amoxicillin component. Due to clavulanic acid component: two 250mg tabs are not equivalent to one 500mg tab.

It has also been suggested that one drug be used to inhibit bacterial penicillinase action sufficiently for ... by competititive inhibition of a β-lactamase have been demonstrated for pseudomonas ...

Cefuroxime has activity in the presence of some beta-lactamases, both penicillinases and cephalosporinases, of Gram-negative and Gram-positive bacteria. Use IV route for serious infections.