The question of how life could have emerged is one of the most long-standing mysteries in science. In a new study, the ...

We suggest that regulated autocatalytic cleavage elements might have a more general function in RNA metabolism ... transcriptional termination, intron degradation and mRNA turnover 22.

A New Mechanism Of Regulating RNA Degradation Date: January 30, 2005 Source: University Of Rochester Medical Center Summary: Lynne E. Maquat, Ph.D., professor of Biochemistry and Biophysics at the ...

The particular ribozymal activity Dr Cech’s team found was an “autocatalytic” rearrangement of an RNA molecule (the actual discovery was made by Paula Grabowski, a graduate student).

"Before the RNA is degraded, these endings, or tails, are progressively removed by the cell machinery. This is the first step in the degradation of RNA molecules that are no longer needed and is ...

Gregory, an Associate Professor in the Department of Biology at Penn, along with postdoctoral fellow Xiang Yu and published in the journal Plant Cell, has elucidated new details on the mechanism of ...

this method turns biologically inactive RNA-binding small molecules into powerful and specific degradation effectors. This research team from the Scripps Research Institute in Jupiter, FL ...

RNA surveillance and degradation pathways exist in all forms of life. From bacteria to humans, all living things have mechanisms to monitor the quality of RNA and to purposely degrade it." ...

Kwak, uncovered a new link between the pathways involved in RNA degradation. Talking about the motivation for their research, Prof Kwak says, "We wanted to investigate novel mechanisms controlling ...

Maquat, Ph.D., professor of Biochemistry and Biophysics at the University of Rochester Medical Center, and her team have identified a novel pathway for RNA degradation, a form of regulation that ...