The loop of Henle has a thin descending limb, a thick ascending limb and a thin ascending limb. The fluid entering the descending limb contains sodium chloride and other salts, urea and other ...

Nat Clin Pract Nephrol. 2008;4(1):38-46. Our knowledge of the localization, function, physiology and pathophysiology of the kidney-specific Cl-channels and Barttin has been greatly extended in the ...

Bumetanide 0.25mg/mL; contains benzyl alcohol. Bumetanide, a loop diuretic, inhibits sodium reabsorption in the ascending limb of the loop of Henle, as shown by marked reduction of free-water ...

Vasopressin increases the rate of active absorption of sodium chloride in the medullary thick ascending limbs ... tubule and thin descending limb of the loop of Henle. 23 In the thin descending ...

Urinary concentration depends on normal function of the countercurrent multiplier, which requires both active transport of sodium chloride in the thick ascending limb of the loop of Henle and ...

In the thick ascending limb of the loop of Henle (Figure 1A), approximately 25% of the filtered solute load is reabsorbed. Transmembrane transport of sodium, potassium and chloride ions from the ...

It works by inhibiting sodium reabsorption in the ascending limb of the loop of Henle. Reabsorption of chloride in the ascending limb is also blocked by bumetanide and potassium excretion is ...

Loop diuretics act at the ascending loop of Henle in the kidney and help the body push out extra fluid that could accumulate in the lungs or legs and ankles when the heart is unable to completely ...

ClC-K1 is predominantly localized to the thin ascending limb of the loop of Henle. ClC-K2 is expressed more broadly in the distal nephron; expression levels are highest along the thick ascending ...