Here we discuss why this is the case and how a cultural shift in the biomedical research community could bring the new technologies for creating antibodies and other tailor-designed binding ...

Antibodies are one ... multiple secondary antibodies binding to a single primary antibody. Secondary antibodies can also be used in Tyramide Signal Amplification (TSA) to further enhance the signal of ...

The variable region confers an antibody's antigen-binding specificity. This region contains two fragment antigen binding (Fab) domains, each capable of binding a specific epitope (the part of an ...

To overcome this challenge, Chung and his colleagues developed CuRVE, wherein they maintained chemical equilibrium throughout the tissue by gradually modulating the speed of antibody-antigen binding.