A protein called the androgen receptor normally functions to guide the development of the prostate—signaling the cells to stop growing, act as normal prostate cells and maintain a healthy state.

Androgens stimulate prostate cancer cells to grow. Many drugs to target that cancer focus on stopping androgen biosynthesis or blocking the androgen receptor, or AR. Researchers have discovered a ...

This study showed that androgen receptors in prostate cells can work as either an accelerator speeding cell growth or a brake inhibiting it. Tumors redirect the receptors' normal activity to press ...

Granulosa Cell-Specific Androgen Receptors Are Critical Regulators of Ovarian Development and Function. Molecular Endocrinology , 2010; DOI: 10.1210/me.2010-0006 Cite This Page : ...

The androgen receptor is simply more versatile in the sets of genes it can turn on compared with other nuclear receptors. In fact, recent findings even suggest that it can affect T cell responses ...

A cell-specific and selective effect on transactivation by the androgen receptor. Exp Cell Res 1995;217:368-377. Crossref. PubMed. Web of Science. Google Scholar. Information & Authors Information ...

The results of the present study, however, indicate that the crosstalk between the androgen and the glucocorticoid receptor suppresses prostate cancer cell division and, consequently, tumor growth.

One of the other, very obvious changes was the breast cells that appear to show the highest level of estrogen receptor signaling were reduced dramatically in proportion to the androgen-treated breast.

The first estrogen receptor was discovered in the late 1950s, a period that Jan-Ǻke Gustafsson refers to as BC (before cloning). Forty years later, he and colleagues were looking for a completely ...