Medically reviewed by Lindsay Cook, PharmDMedically reviewed by Lindsay Cook, PharmD Low alkaline phosphatase (ALP) can be a sign of several different conditions, including thyroid disease ...

Alkaline phosphatase refers to a group of phosphatases (pH optimum approximately 10) found in almost every tissue in the body. Most alkaline phosphatase in normal adult serum is from the liver or ...

Ipsen’s elafibranor has shown promise as a treatment for primary sclerosing cholangitis (PSC), a rare liver disease that ...

In these videos, Sushila Dulal, MD, associate professor of medicine at the University Chicago of Medicine, discusses the latest treatments, state of the pipeline and unmet needs for patients with ...

Juvenile Paget disease (JPD) is a very rare disease, mainly caused by biallelic inactivating mutations in the TNFRSF11B gene that encodes osteoprotegerin. Owing to its rarity, the treatment of JPD is ...

However, it did not produce significant change in the levels of alkaline phosphatase (ALP), an enzyme associated with liver disease, which meant the trial was stopped due to lack of treatment ...

The researchers measured serum concentrations of PTH, two bone formation markers (bone-specific alkaline phosphatase and intact osteocalcin) and two bone resorption markers (TRACP5b and N-terminal ...