Using radioactivity, he managed to unveil several receptors, including one for adrenalin, the β-adrenergic receptor. His team then extracted the receptor from the cell membrane and forged an initial ...

The addition of β-adrenergic receptor antagonists to a medical regimen for heart failure that includes angiotensin-converting enzyme (ACE) inhibitors as background therapy has been associated ...

Pounding heart, tight muscles, and rapid breathing are all familiar effects of the “fight or flight” response. Adrenaline receptors turn on protein kinase A (PKA), which opens calcium channels in ...

The binding of adrenaline to an adrenergic receptor initiates a cascade of reactions inside the cell. The signal transduction cascade begins when adenylyl cyclase, a membrane- bound enzyme ...

In this study, researchers first revealed that α 2A-adrenergic receptor (ADRA2A) is a highly expressed G-protein-coupled receptor (GPCR) in ISCs. Through PRESTO-Tango and BRET2 GPCR assays ...

Alpha receptor agonists are substances that activate the sympathetic nervous system by stimulation of alpha receptors, similar to the effects of epinephrine and norepinephrine. Alpha receptors are ...

"G-protein-coupled receptors are ubiquitous in the function of cells in the body and help us to sense light, flavour and odour. They are also responsible for the human body's reactions to chemicals in ...