Naturally rewarding stimuli (i.e. food, sex, etc) increase the activity of dopamine cells in the mesocorticolimbic dopamine system causing increased dopamine release in brain areas such as the nucleus ...

A new study finds that RNA editing by ADAR1 in astrocytes contributes to neuroinflammation in Parkinson’s disease. Using ...

It also develops Quemliclustat, a small molecule inhibitor that targets the CD73 enzyme in the ATP-adenosine pathway ... a dual A2a/A2b adenosine receptor antagonist, which is in phase 2 clinical ...

The half-life is 6 seconds. Adenosine receptor activation results in multiple different actions depending on the location. Adenosine plays an important role in energy transfer (adenosine ...