Obesity is associated with an increased risk of developing breast cancer, and a greater probability for the cancer to spread ...

Platelets circulate within the whole body and exert two principle functions: protection against bleeding and invading pathogens. Their multiple antimicrobial facets are beneficial, such as direct ...

When skin is cut or damaged, tiny cell fragments circulating in the blood, called platelets, arrive at the injury and spread ...

The currently available antiplatelet drugs target key steps of platelet activation including thromboxane A 2 synthesis, ADP-mediated signaling, and glycoprotein IIb/IIIa-mediated platelet aggregation.

A team led by the Spanish National Cancer Research Centre (CNIO) has shown in mice that a high-fat diet increases metastasis of triple-negative breast cancer, which has the worst prognosis.

five showed a marked decrease in platelet adhesiveness, four showed an abnormality in the thromboplastin generation test at the four-minute activation time, and two had a prolongation of the ...

Class, Polyphosphate (polyP)-Based Therapy, Show Promise in Bypassing P2Y12 Inhibition to Restore Normal Clotting Function ...

A BLA has been filed for bentracimab and, if approved, has the potential to be the first therapy to reverse the effects of ...

Until recently, researchers believed that platelet spreading and clot contraction were controlled by the same pathway. However a recent study from Thomas Jefferson University researchers challenges ...

CNIO researchers discover that, in mice that eat a lot of fat, cancer cells travelling through the blood surround themselves with platelets, which act as an armor-like protection as they spread. In ...