Figure 2. The oxidation of both acetaminophen and p-phenylenediamine leads to short-lived, highly reactive toxins. The most reactive part of each molecule is indicated by a red plus sign. The ...

“Acetaminophen’s chemical structure and the way it breaks down seems to have a similar backbone to phthalates,” said NYU’s Trasande, who researches the impact of chemicals on babie ...

She focused on altering the molecule’s benzene ring, a crucial part of acetaminophen’s chemical structure, and discovered that her modification could reduce acetaminophen’s chemical ...

More information: James Chun Yip Chan et al, Reactive Metabolite-induced Protein Glutathionylation: A Potentially Novel Mechanism Underlying Acetaminophen Hepatotoxicity, Molecular & Cellular ...

The team derived acetaminophen ... down to its molecular backbones before being built back into the desired compound, the lignin-based molecules already bear some of the desired structure.

Much controversy surrounds the pathogenesis of acetaminophen-induced inflammation ... is active as a damage-associated molecular pattern (DAMP). After enzymatic cleavage, mature IL-1α can ...