A new, streamlined AAV purification process that is both universal and scalable could ease commercialization constraint.

Of particular concern is the virus’s liking for the liver. “If you look at the number of ... and compared delivery efficiencies of the GFP molecules across the brain. AAV-PHP.B showed at least 40-fold ...

Potent in vivo gene editing in skeletal muscle of non-human primates by a novel, ultracompact CRISPR system delivered via a single AAV vector.

Using this model, the researchers generated proteins with mutations that were predicted to lead to improved versions of GFP and a protein from adeno-associated virus (AAV), which is used to ...